"Surface Enhanced Raman Spectroscopy for bioanalytical sensing", by Sebastian Wachsmann-Hogiu
The Friday, June 23, 2017
at 3:00 PM
F021b,
Building F,
Laboratoire Hubert Curien,
18 Rue Professeur Benoît Lauras,
42000 Saint-Etienne
Seminar by Prof. Sebastian Wachsmann-Hogiu, Professor at McGill University (Montreal, Canada)
Abstract
Surface Enhanced Raman Spectroscopy (SERS) is a technique that has the potential for multiplexed detection and quantification of analytes of interest. The preparation and characterization of various SERS substrates will be presented, including colloidal nanoparticles, 2D, and 3D substrates. Flexible substrates, as well as substrates based on common consumer products such as CDs and DVDs will be presented. Next, different fundamental approaches to biosensing will be discussed, including label free and functional assays. Applications to detection of biomolecules as well as to small biological particles such as exosomes will be demonstrated. As SERS evolves towards single molecule level sensitivities, main requirements for quantitation at low molecular counts will be discussed.
Bio
Sebastian Wachsmann-Hogiu received his PhD in 2000 from Humboldt University in Berlin. After a two years postdoctoral stage at Carnegie Mellon University, he moved to Cedars Sinai Medical Center in Los Angeles, and in 2007 at the University of California Davis, where he advanced to full Professor in 2015. In 2016 he was also a Principal Investigator at Intellectual Ventures/Global Good, Bellevue, WA. Since January 2017 he is a Professor in the Department of Bioengineering at McGill University, Montreal Canada. His main research interests are in the fields of advanced microscopy and spectroscopy and point of care technologies.
The seminar will be held in English.